DGAP-News: American Medical Technologies (North American) Ltd.
(firmenpresse) - American Medical Technologies (North American) Ltd. / Miscellaneous
12.04.2010 08:45
Dissemination of a Corporate News, transmitted by
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MANALAPAN, NJ, USA - April 12, 2010 - American Medical Technologies, Inc.
(WKN A0RM18, AMT, M20 Frankfurt Exchange) announced today that proprietary
Blood Cell Morphometric Method (BCMM) technology was implemented using
inspection system Prototype AMT 007 to find and measure lymphocytes nuclei
and cytoplasm dimensions. This data collected by motorized microscope
system is key lymphocytes statistics used for determination of cancer
disease and its stage.
Lymphocytes are quite common in the blood: 20-40%, 8-10µm in diameter and
generally they are smaller than the other leukocytes but they are still
a few larger than red cells. The cytoplasm is transparent. The nucleus is
round and large in comparison to the cell and it occupies most of it.
Our Prototype is fully automated system consists of Nikon Eclipse 50i
microscope with Ludl BioPoint 2 motorized XY stage and motorized focus Z
stage with linear encoder to achieve focus resolution up to 0.1 micron.
Extremely high positional accuracy for the focusing lens is essential to
achieve accurate measurement results fully correlated with original manual
inspection results. It is also important for production system collecting
images with continuous movement of the XY stage. Software choice for quick
development of prototype system was Media Cybernetics, Inc. IMAGE-PRO bio-
medical software. It is well known by FDA and bio-medical research
scientists.
Motorized XYstage moves a glass smear under the microscope and digital
camera (QICAM) captures one by one frame located close to each other.
Distance between neighbor frames is approximately 30% of frame width and
height to avoid repeatable measurement of the same cells located on the
borders. Nuclei color (usually dark blue) is unique for the image. The
first part of inspection is to find nuclei color objects (or BW level
objects) satisfying the dimensional limits for nuclei. Only lymphocytes
with oval single nuclei 4 to 12 micron in size will be considered in
collected data. Roundness characteristics of the nuclei help us to reject
other types of cells (different than lymphocytes). Statistics shows that 15
to 20% of lymphocytes will be detected on the borders of the frame and
system moves these cells to the center of the camera Field of View (FOV).
More complicated task is to finda cytoplasm, but we are looking for one in
the area concentric to the nuclei center. This eliminates possible foreign
cells located in proximity to the nuclei. Positional information of cells
collected and stored automatically on the PC hard drive. Inspection of the
smear can be repeated with the same or higher resolution camera and even
higher magnification lens based on positional information. Our Prototype
system can also visually sort cells images and eliminate all unnecessary
data and algorithms can be used in next generation of our production
system.
About American Medical Technologies, Inc.
American Medical Technologies discovers and develops
patented Blood Cell Morphometric Method TM (BCMM) which became one of the
first companies to realize the new science'spromise by bringing safe and
effective method for cancer diagnostic. AMT committed to change the
practice of medicine, helping millions of people around the world in the
fight against cancer, kidney disease, rheumatoid arthritis and other
serious illnesses. AMT remains committed to advancing science to
dramatically improve people's lives. To learn more about our pioneering
science and our approach, visit www.americanmedtech.com
For Investor Relations please contact our offices at
1-800-239-5AMT (5268) or by e-mail investor(at)americanmedtec.com
12.04.2010 08:45 Ad hoc announcement, Financial News and Media Release distributed by DGAP. Medienarchiv atwww.dgap-medientreff.deandwww.dgap.de---------------------------------------------------------------------------
Bereitgestellt von Benutzer: EquityStory
Datum: 12.04.2010 - 08:45 Uhr
Sprache: Deutsch
News-ID 18828
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