TopiVert to Present First in Human Data From Its Phase I Clinical Study With TOP1288 at DDW 2016 in San Diego
(firmenpresse) - LONDON, UNITED KINGDOM -- (Marketwired) -- 05/09/16 -- ("TopiVert" or the "Company"), a clinical-stage biotechnology company developing Narrow Spectrum Kinase Inhibitors (NSKIs) as novel, locally-acting medicines for the treatment of chronic inflammatory diseases of the gastrointestinal tract and eye, announces that it will present posters on the Phase I study data results and pre-clinical pharmacology for TOP1288, its lead compound for the treatment of ulcerative colitis (UC), a form of inflammatory bowel disease (IBD), at the Digestive Disease Week (DDW) 2016 in San Diego, California, from 21-24 May.
Senior members of the management and R&D teams will be available at the conference to discuss the data with interested parties. The posters to be presented are:
A first-in-human randomized double-blind placebo-controlled clinical trial of a novel narrow spectrum kinase inhibitor. Rowley et al.
TOP1210 NSKI Demonstrates Superior Activity and Improved Safety Profile Potential Compared to Corticosteroid and Immunomodulators in Preclinical Models of Colitis. Walshe et al.
Inhibition of cytokine release from HT-29 cells and ulcerative colitis biopsies is potentiated by combination of selective kinase inhibitors and such effects are mimicked by TOP1210, a Narrow spectrum kinase inhibitor (NSKI). Foster et al.
Effects of TOP1210, a narrow spectrum kinase inhibitor, and selective kinase inhibitors on the intestinal pro-inflammatory immune response in ulcerative colitis. Foster et al.
The posters are all available at
Click on, or paste the following link into your web browser, to view the associated PDF document.
This information is provided by RNS
The company news service from the London Stock Exchange
Steve Webber
Chief Scientific Officer
+44 (0)20 3763 9468
Nick Staples
Business and Corporate Development
+44 (0)7818 075 816
Mary-Jane Elliott / Ivar Milligan / Hendrik Thys
+44 (0)20 3709 5700
Themen in dieser Pressemitteilung:
Unternehmensinformation / Kurzprofil:
Datum: 09.05.2016 - 06:00 Uhr
Sprache: Deutsch
News-ID 469399
Anzahl Zeichen: 0
contact information:
Town:
LONDON, UNITED KINGDOM
Kategorie:
Healthcare
Diese Pressemitteilung wurde bisher 278 mal aufgerufen.
Die Pressemitteilung mit dem Titel:
"TopiVert to Present First in Human Data From Its Phase I Clinical Study With TOP1288 at DDW 2016 in San Diego"
steht unter der journalistisch-redaktionellen Verantwortung von
TopiVert Pharma Limited (Nachricht senden)
Beachten Sie bitte die weiteren Informationen zum Haftungsauschluß (gemäß TMG - TeleMedianGesetz) und dem Datenschutz (gemäß der DSGVO).
