New analysis with Alpharadin to be presented at 2011 Genitourinary Cancers Symposium
(Thomson Reuters ONE) -
Oslo, Norway, 16 February 2011 - Algeta ASA (OSE: ALGETA), a company focused on
the development of novel targeted cancer therapeutics, notes that a new analysis
of clinical data from its phase II clinical program with Alpharadin will be
presented at the 2011 Genitourinary Cancers Symposium* in Orlando, FL, USA (17-
19 February 2011).
The analysis concluded that the effect of Alpharadin (radium-223) on normalizing
serum markers of bone metabolism, including alkaline phosphatase (ALP), in
patients with bone metastases from castration-resistant prostate cancer is
associated with significantly better overall survival.
Poster title: Alkaline phosphatase (ALP) normalization and overall survival in
patients with bone metastases from castration-resistant prostate cancer (CRPC)
treated with radium-223.
Presented by Dr. Christopher Parker (Institute of Cancer Research and Royal
Marsden Hospital, Sutton, UK)
Abstract #49
Thursday 17 February, 11:45-13:00 (ET)
General Poster Session A: Prostate Cancer
Orlando World Center Marriott
*The 2010 Genitourinary Cancers Symposium is being co-sponsored by three leading
medical specialty societies, including the American Society of Clinical Oncology
(ASCO), the American Society for Radiation Oncology (ASTRO) and the Society of
Urologic Oncology (SUO).
###
For further information, please contact
Andrew Kay, CEO +47 2300 7990 / +47 4840 1360 (mob)
Øystein Soug, CFO +47 2300 7990 / +47 9065 6525 (mob)
post(at)algeta.com
International media enquiries: +44 207 638 9571
Mark Swallow/David Dible mark.swallow(at)citigatedr.co.uk
Citigate Dewe Rogerson
US investor enquiries: +1 646 378 2928
Jessica Lloyd jlloyd(at)troutgroup.com
The Trout Group
About Algeta
Algeta is a company focused on developing novel targeted therapies for patients
with cancer based on its alpha-pharmaceutical platform.
Algeta's lead product Alpharadin (based on radium-223) is a first-in-class,
highly targeted alpha-pharmaceutical under clinical evaluation to improve
survival in patients with bone metastases from advanced cancer. Its localized
action helps preserve the surrounding healthy tissue thereby limiting side-
effects.
The development of bone metastases represents a serious development for cancer
patients as they are associated with a dramatic decline in patient health and
quality of life, ultimately leading to death. Bone metastases represent a major
unmet medical need, occurring in up to 90% of certain late-stage cancers, e.g.
prostate, breast and lung.
Alpharadin is being developed under a development and commercialization
agreement with Bayer Schering Pharma AG, a major pharmaceutical company, and is
in a global phase III clinical trial (ALSYMPCA) to treat bone metastases
resulting from castration-resistant prostate cancer (CRPC). Alpharadin is also
under investigation in phase II clinical trials as a potential new treatment for
bone metastases in endocrine-refractory breast cancer patients, and in a phase
I/IIa trial in combination with docetaxel chemotherapy in for bone metastases
CRPC patients.
Algeta also aims to develop a future pipeline of tumor-targeting alpha-
pharmaceutical candidates based on the alpha particle emitter thorium-227,
through selective in-licensing and/or acquiring innovative technologies and
tumor-targeting molecules.
The Company is headquartered in Oslo, Norway, and was founded in 1997. Algeta
listed on the Oslo Stock Exchange in March 2007 (Ticker: ALGETA).
Alpharadin and Algeta are trademarks of Algeta ASA.
Forward-looking Statement
This news release contains forward-looking statements and forecasts based on
uncertainty, since they relate to events and depend on circumstances that will
occur in the future and which, by their nature, will have an impact on results
of operations and the financial condition of Algeta. There are a number of
factors that could cause actual results and developments to differ materially
from those expressed or implied by these forward-looking statements. These
factors include, among other things, risks associated with technological
development, the risk that research & development will not yield new products
that achieve commercial success, the impact of competition, the ability to close
viable and profitable business deals, the risk of non-approval of patents not
yet granted and difficulties of obtaining relevant governmental approvals for
new products.
This information is subject of the disclosure requirements acc. to §5-12 vphl
(Norwegian Securities Trading Act)
Press release:
http://hugin.info/134655/R/1489553/425097.pdf
This announcement is distributed by Thomson Reuters on behalf of
Thomson Reuters clients. The owner of this announcement warrants that:
(i) the releases contained herein are protected by copyright and
other applicable laws; and
(ii) they are solely responsible for the content, accuracy and
originality of the information contained therein.
Source: Algeta ASA via Thomson Reuters ONE
[HUG#1489553]
Unternehmensinformation / Kurzprofil:
Datum: 16.02.2011 - 13:00 Uhr
Sprache: Deutsch
News-ID 51562
Anzahl Zeichen: 5948
contact information:
Town:
Oslo
Kategorie:
Business News
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"New analysis with Alpharadin to be presented at 2011 Genitourinary Cancers Symposium"
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