MorphoSys Strengthens European Patent Position on anti-CD19 Cancer Program MOR208
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MorphoSys AG /
MorphoSys Strengthens European Patent Position on anti-CD19 Cancer Program
MOR208
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MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX, OTC: MPSYY) announced
today that the European Patent Office has granted a patent covering the
Company's cancer compound MOR208. The new patent (EP2383297) covers the
antibody's protein and nucleic acid sequences as well as pharmaceutical
compositions comprising the same. The new patent has a scheduled expiry date in
2027, not including any potential patent office or regulatory extensions, and is
licensed to MorphoSys AG from Xencor, Inc.
Dr. Marlies Sproll, Chief Scientific Officer of MorphoSys AG, commented: "MOR208
will be a key focus area for our development activities in the years to come and
thus patent protection in the most relevant markets is of significant
importance. Today's patent complements a new US patent covering the MOR208
antibody, which we announced a few weeks ago."
MOR208 is a humanized monoclonal antibody that targets the antigen CD19 for
treatment of B cell malignancies and autoimmune diseases. The antibody has been
engineered to possess significantly enhanced antibody-dependent cell-mediated
cytotoxicity (ADCC), thus improving a key mechanism for tumor cell killing and
offering potential for enhanced efficacy compared to traditional antibodies for
the treatment of cancer.
MOR208 has shown encouraging signs of preliminary anti-tumor activity and an
acceptable safety and tolerability profile in a Phase 1/2a trial in patients
with high-risk, heavily pretreated chronic lymphocytic leukemia (CLL) or small
lymphocytic lymphoma (SLL). The study results showed an overall response rate of
29.6% (according to IWCLL 2008 criteria) based on the safety population of the
trial (n=27). MorphoSys is conducting Phase 2 clinical trials of MOR208 in
patients with non-Hodgkin's lymphoma (NHL) and B-cell acute lymphoblastic
leukemia (B-ALL).
About MorphoSys:
MorphoSys developed HuCAL, the most successful antibody library technology in
the pharmaceutical industry. By successfully applying this and other patented
technologies, MorphoSys has become a leader in the field of therapeutic
antibodies, one of the fastest-growing drug classes in human healthcare.
Together with its pharmaceutical partners, MorphoSys has built a therapeutic
pipeline of more than 80 human antibody drug candidates for the treatment of
cancer, rheumatoid arthritis, and Alzheimer's disease, to name just a few. With
its ongoing commitment to new antibody technology and drug development,
MorphoSys is focused on making the healthcare products of tomorrow. MorphoSys is
listed on the Frankfurt Stock Exchange under the symbol MOR. For regular updates
about MorphoSys, visit http://www.morphosys.com
HuCAL®, HuCAL GOLD®, HuCAL PLATINUM®, CysDisplay®, RapMAT®, arYla® and Ylanthia®
and 100 billion high potentials® are registered trademarks of MorphoSys AG.
Slonomics® is a registered trademark of Sloning BioTechnology GmbH, a subsidiary
of MorphoSys AG.
This communication contains certain forward-looking statements concerning the
MorphoSys group of companies. The forward-looking statements contained herein
represent the judgment of MorphoSys as of the date of this release and involve
risks and uncertainties. Should actual conditions differ from the Company's
assumptions, actual results and actions may differ from those anticipated.
MorphoSys does not intend to update any of these forward-looking statements as
far as the wording of the relevant press release is concerned.
For more information, please contact:
MorphoSys AG
Dr. Claudia Gutjahr-Löser
Head of Corporate Communications & IR
Tel: +49 (0) 89 / 899 27-122
Mario Brkulj
Associate Director Corporate Communications & IR
Tel: +49 (0) 89 / 899 27-454
Alexandra Goller
Specialist Corporate Communications & IR
Tel: +49 (0) 89 / 899 27-332
investors(at)morphosys.com
Media Release (PDF):
http://hugin.info/130295/R/1747040/588214.pdf
This announcement is distributed by GlobeNewswire on behalf of
GlobeNewswire clients. The owner of this announcement warrants that:
(i) the releases contained herein are protected by copyright and
other applicable laws; and
(ii) they are solely responsible for the content, accuracy and
originality of the information contained therein.
Source: MorphoSys AG via GlobeNewswire
[HUG#1747040]
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