Taconic Biosciences Expands Microbiome Portfolio

Taconic Biosciences Expands Microbiome Portfolio

ID: 540504

(Thomson Reuters ONE) -


Germ Free BALB/c Mice Facilitate Discovery of New Therapeutics

HUDSON, N.Y., May 04, 2017 (GLOBE NEWSWIRE) -- Taconic Biosciences, global
leader in genetically engineered mouse models and associated services and the
only commercial provider of germ-free mice, announced it has added Germ Free
BALB/c mice to its microbiome portfolio.  The new product expands Taconic's
existing collection of germ-free animal models, which includes C57BL/6 (Black
6) and Swiss Webster mice.

The BALB/c inbred strain is commonly used for antibody production and vaccine
efficacy studies.  It is also widely used in adoptive transfer studies such as
adoptive transfer colitis models and syngeneic tumor studies for immuno-oncology
research. Taconic offers Germ Free BALB/c mice as an off-the-shelf product, with
study cohorts available for immediate worldwide delivery.

"BALB/c have been an unmet need in terms of germ-free strain availability," said
Dr. Alexander Maue, Taconic's portfolio director for microbiome products and
services. "The BALB/c inbred strain displays Th2-biased immune responses, as
opposed to the Th1 bias in C57BL/6 mice, opening a whole new range of studies.
Availability of germ-free mice in quantities relevant for drug discovery
accelerates development of microbiome-focused therapeutics."

Germ-free mice, also referred to as axenic mice, contain no microflora. These
mice can be associated with specific human or mouse flora, or mono-associated
with particular bacteria. Germ-free mice are the ideal substrate for
performing fecal microbiota transplants (FMT), a service provided by Taconic.
Following FMT, Taconic also offers husbandry services to accommodate studies of
all sizes and lengths including options for isolators and state-of-the-art
individually ventilated cages (IVCs).

Study of the microbiome has become a prime focus of drug discovery, as evidence




mounts demonstrating the connection between a person's flora and their
health. Science magazine named the microbiome their breakthrough of the year in
both 2011 and 2013 and the microbiome topped Cleveland Clinic's medical
innovations list for 2016. Taconic's microbiome platform provides key products
and services to study this connection.

To learn more about Taconic's microbiome solutions,
visit Taconic.com/microbiome or contact us at 1-888-TACONIC (888-822-6642) in
the US, +45 70 23 04 05 in Europe, or at info(at)taconic.com.

About Taconic Biosciences, Inc.

Taconic Biosciences is a fully-licensed, global leader in genetically engineered
rodent models and services. Founded in 1952, Taconic helps biotechnology
companies and institutions acquire, custom generate, breed, precondition, test,
and distribute valuable research models worldwide.  Specialists in genetically
engineered mouse and rat models, precision research mouse models, and integrated
model design and breeding services, Taconic operates three service laboratories
and six breeding facilities in the U.S. and Europe, maintains distributor
relationships in Asia and has global shipping capabilities to provide animal
models almost anywhere in the world.

Media Contact:
Kelly Owen Grover
Director of Marketing Communications
(518) 697-3824
kelly.grover(at)taconic.com




This announcement is distributed by Nasdaq Corporate Solutions on behalf of Nasdaq Corporate Solutions clients.
The issuer of this announcement warrants that they are solely responsible for the content, accuracy and originality of the information contained therein.

Source: Taconic Biosciences via GlobeNewswire




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Datum: 04.05.2017 - 21:57 Uhr
Sprache: Deutsch
News-ID 540504
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